Current Status of Intestinal Schistosomiasis in Two Different Rural Settings, Kafr El-Sheikh Governorate, Egypt.
DOI:
https://doi.org/10.4314/njpar.v46i1.9%20Keywords:
Schistosomiasis, Prevalence, Intensity, Risk factors, EgyptAbstract
Schistosomiasis is a neglected tropical disease that has been selected for elimination. Egypt is one of the endemic areas for Schistosoma mansoni. Preventive programmes have been adopted to fight schistosomiasis with great progress. This study aimed to assess the status of intestinal schistosomiasis among residents of two rural endemic settings in Kafrelsheikh Governorate, Egypt and evaluate the associated risk factors for infection. A cross-sectional study was conducted on 437 residents from El-Roos and El-Salahba villages aged from 5 to 30 years. Stool samples were examined for the presence of S. mansoni using the Kato-Katz stool thick smear technique. The prevalence of S. mansoni was 14.4% among participants of El-Salahba, however, no solitary case was detected in ElRoos. Most infected children (80.6%) had light-intensity of schistosomiasis. A statistically significant association was detected between Schistosoma infection and gender (OR=2.302, 95% CI: 1.107–4.785, p < 0.026), canal water contact (OR=4.388, 95% CI: 2.071 – 9.297, p < 0.001), skin itching (OR=3.312, 95% CI: 1.606 – 6.826, p = 0.001), the presence of abdominal pain (OR=2.523, 95% CI:1.057 – 6.025, p = 0.037), and the presence of blood in stools (OR=11.044, 95% CI: 4.636 – 26.311, p < 0.001). Continuous monitoring and evaluation of the prevalence of schistosomiasis are crucial for control programs.
References
WHO(2013). Schistosomiasis: progress report 2001-2011, strategic plan 2012-2020.
Deol, A. K., Fleming, F. M., Calvo-Urbano, B., Walker, M., Bucumi, V., Gnandou, I., Tukahebwa, E. M., Jemu, S.,Mwingira, U. J., Alkohlani, A., Traoré, M., Ruberanziza, E., Touré, S., Basáñez, M. G., French, M. D., & Webster J.P. (2019). Schistosomiasis - Assessing Progress toward the 2020 and 2025 Global Goals. New England Journal of Medicine, 381(26):2519-2528. doi:10.1056/NEJMoa1812165
Sady, H., Al-Mekhlafi H. M., Mahdy M. A., Lim Y. A., Mahmud R., & Surin J. (2013). Prevalence and associated factors of Schistosomiasis among children in Yemen: implications for an effective control programme. PLoS Neglected Tropical Diseases, 7(8):e2377. doi:10.1371/journal.pntd.0002377
Hotez, P. J., Alvarado, M., Basáñez, M. G., Bolliger, I., Bourne, R., Boussinesq, M., Brooker, S. J., Brown, A. S., Buckle, G., & Budke, C. M. (2014). The global burden of disease study 2010: interpretation and implications for the neglected tropical diseases. PLoS Neglected Tropical Diseases, 8(7):e2865
El Naga, I. F., Eissa, M. M., Mossallam, S. F., & El-Halim, S. I. (2010). Inheritance of Schistosoma mansoniinfection incompatibility in Biomphalaria alexandrina snails. Memórias do Instituto Oswaldo Cruz, 105(2):149-154. doi:10.1590/s0074-02762010000200007
El-Khoby, T., Galal, N., Fenwick, A., Barakat, R., El-Hawey, A., Nooman, Z., Habib, M., Abdel-Wahab, F., Gabr, N. S., Hammam, H. M., Hussein, M. H., Mikhail, N. N., Cline, B. L., & Strickland, G. T. (2000). The epidemiology of schistosomiasis in Egypt: summary findings in nine governorates. American Journal of Tropical Medicine and Hygiene, 62(2 Suppl):88-99. doi:10.4269/ajtmh.2000.62.88
McManus, D. P., Dunne, D. W., Sacko, M., Utzinger, J., Vennervald, B. J., & Zhou, X. N. (2018). Schistosomiasis. Nature Reviews Disease Primers, 4(1):13. doi:10.1038/s41572-018-0013-8
Elhadad, H., Mohamed, M. A., Mohamed, M. M., & Abdo, S. (2022). Evaluation of faecal lactoferrin as a morbidity biomarker in Schistosoma mansoni infection. Tropical Medicine and International Health, 27(12):1053-1058. doi:10.1111/tmi.13826
Katz, N., Chaves A., & Pellegrino J. (1972). A simple device for quantitative stool thick-smear technique in Schistosomiasis mansoni. Revista do Instituto de Medicina Tropical de São Paulo, 14(6):397-400
Bezerra, F.S.M., Leal J.K.F., Sousa M.S., Pinheiro M.C.C., Ramos A.N., Jr., Silva-Moraes V., and Katz N. (2018). Evaluating a point-of-care circulating cathodic antigen test (POC-CCA) to detect Schistosoma mansoni infections in a low endemic area in north-eastern Brazil. Acta Tropica, 182:264-270. doi:10.1016/j.actatropica.2018.03.002
Barakat, R. M.(2013). Epidemiology of Schistosomiasis in Egypt: Travel through Time: Review. Journal of Advanced Research, 4(5):425-432. doi:10.1016/j.jare.2012.07.003
Elmorshedy, H., Bergquist, R., Fayed, A., Guirguis, W., Abdel-Gawwad, E., Eissa, S., and Barakat, R. (2020). Elimination of schistosomiasis requires multifactorial diagnostics: evidence from high- and low-prevalence areas in the Nile Delta, Egypt. Infectious Diseases of Poverty, 9(1):31. doi:10.1186/s40249-020-00648-9
Ghazy, R. M., Tahoun, M. M., Abdo, S. M., El-Badry, A. A., and Hamdy, N. A. (2020). Evaluation of Praziquantel Effectiveness After Decades of Prolonged Use in an Endemic Area in Egypt. Acta Parasitology. doi:10.1007/s11686-020-00242-x
World Health Organization (2002). Prevention and control of schistosomiasis and soil-transmitted helminthiasis. World Health Organization Technical Reports Series 912:i-vi, 1-57 https://www.who.int/publications/i/item/WHOTRS-912
Kirkpatrick, L. A., & Feeney B. C. (2013). A simple guide to IBM SPSS statistics for version 20.0. Student ed. Belmont, Calif.: Wadsworth, Cengage Learning.
Colley, D. G., Bustinduy, A. L., Secor, W. E., & King, C. H. (2014). Human schistosomiasis. Lancet 383 (9936):2253-2264. doi:10.1016/s0140-6736(13)61949-2
World Health Organization (2006) Preventive chemotherapy in human helminthiasis. Coordinated use of anthelminthic drugs in control interventions: a manual for health professionals and programme managers. https://iris.who.int/bitstream/handle/10665/43545/9241547103_eng.pdf?sequence=1
World Health Organization (2022). World Health Organization Schistosomiasis, fact sheets.
https://www.who.int/news-room/fact-sheets/detail/schistosomiasis
Allam, A. F., Salem, A., Elsheredy, A., Dewair, M. M., Ibrahim, H. S., Farag, H. F., Hagras, N. A., & Shehab, A. Y. (2021). Intestinal schistosomiasis among preschool and school-aged children in a rural setting near Alexandria: initiative for elimination. Tropical Medicine and International Health, 26(6):632-639. doi:10.1111/tmi.13562
Haggag, A. A., Rabiee, A., Abd Elaziz, K. M., Gabrielli, A. F., Abdel Hay, R., & Ramzy, R. M. R.(2017). Mapping of Schistosoma mansoni in the Nile Delta, Egypt: Assessment of the prevalence by the circulating cathodic antigen urine assay. Acta Tropica 167: 9-17. doi:10.1016/j.actatropica.2016.11.038
Shehab, A. Y., Allam A. F., Elhadad H., Shoughy M. S., Moneer E. A., & Farag H. F. (2021). A study on positive school children as indicators of schistosomiasis status in their families. Journal of Parasitic Diseases, 45(2):298-301.doi:10.1007/s12639-020-01317-2
Elmorshedy, H., Bergquist, R., El-Ela, N. E., Eassa, S. M., Elsakka, E. E., & Barakat, R. (2015). Can human schistosomiasis mansoni control be sustained in high-risk transmission foci in Egypt? Parasites & Vectors, 8:372. doi:10.1186/s13071-015-0983-2
Ghazy, R. M., Ellakany, W. I., Badr, M. M., Taktak, N. E. M., Elhadad, H., Abdo, S. M., Hagag, A., Hussein, A. R., & Tahoun, M. M. (2022). Determinants of Schistosoma mansoni transmission in hotspots at the late stage of elimination in Egypt. Infectious Diseases of Poverty, 11(1):102. doi:10.1186/s40249-022-01026-3
Trienekens, S. C. M., Faust C.L., Meginnis K., Pickering L., & Ericsson O. (2020). Impacts of host gender on Schistosoma mansoni risk in rural Uganda- A mixed-methods approach. PLoS Neglected Tropical Diseases, 14(5):e0008266. doi:10.1371/journal.pntd.0008266
Cabello, R., Beck, L., Massara, C. L., Murta, F. L. G., Guimarães, R., Pieri, O. S., Schall, V. T., & Favre, T. C. (2016). Schistosoma mansoni infection and related knowledge among schoolchildren in an endemic area of Minas Gerais, Brazil, prior to educational actions. Acta Tropica, 164:208-215. doi:10.1016/j.actatropica.2016.09.015
Afifi, A., Ahmed, A. A. A., Sulieman, Y., & Pengsakul, T.(2016). Epidemiology of schistosomiasis among villagers of the New Halfa Agricultural Scheme, Sudan. Iranian journal of parasitology, 11(1):110
N’Zi, C. K., Ouattara, M., Assaré, R. K., Bassa, F. K., Diakité, N. R., & N’Goran, E. K. (2021). Risk Factors and Spatial Distribution of Schistosoma mansoni Infection among Preschool-Aged Children in Blapleu, Biankouma District, Western Cˆote d’Ivoire. Journal of Tropical Medicine 2021: 6224401.
Gambo, S., Ibrahim, M., Oyelami, O. A., & Raymond, B.(2021). Acomparative study on the prevalence and intensity of urinary schistosomiasis among primary (formal) and Almajiri (informal) school pupils in Kura local government area of Kano State, Nigeria. Nigerian Postgraduate Medical Journal, 28(3):211-217. doi:10.4103/npmj.npmj_605_21
Alemayehu, B., & Tomass, Z. (2015). Schistosoma mansoni infection prevalence and associated risk factors among schoolchildren in Demba Girara, Damot Woide District of Wolaita Zone, Southern Ethiopia. Asian Pacific Journal of Tropical Medicine, 8(6):457-463. doi:10.1016/j.apjtm.2015.05.009
Nigo, M. M., Odermatt, P., Nigo, D. W., Salieb-Beugelaar, G. B., Hunziker, P. R., & Battegay, M. (2021). Morbidity associated with Schistosoma mansoni infection in north-eastern Democratic Republic of the Congo. PLoS Neglected Tropical Diseases 15(12):e0009375. doi:10.1371/journal.pntd.0009375
Betson, M., Sousa-Figueiredo, J. C., Rowell, C., Kabatereine, N. B., & Stothard, J. R. (2010). Intestinal schistosomiasis in mothers and young children in Uganda: investigation of field-applicable markers of bowel morbidity. American Journal of Tropical Medicine and Hygiene, 83(5):1048-1055. doi:10.4269/ajtmh.2010.10-0307
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