Concurrent Hepatozoonosis and Transmissible Venereal Tumour in a 10-Year Old German Shepherd Dog In Abeokuta, Nigeria
https://doi.org/10.4314/njpar.v42i1.9
Keywords:
Dog, hepatozoonosis, TVT, unresponsive to chemotherapyAbstract
In this study, a case of hepatozoonosis with concurrent TVT unresponsive to chemotherapy in a 10-year old female German shepherd dog treated with Vincristine for 10 weeks at the State Veterinary Clinic, Abeokuta, was referred to the Veterinary Teaching Hospital, Federal University ofAgriculture,Abeokuta, Nigeria.Adiagnosis of hepatozoonosis and TVT were made based on clinical presentations including protruding mass from the vulva, parasitological technique and cytological evaluation of the tumour mass and bone marrow using optical fine needle aspirate. Pathological changes observed in various organs at post-mortem, following euthanasia were cachexia, pale and icteric ocular and oral mucous membranes, enlarged and oedematous lymph nodes. Histopatholgical lesions were round to oval neoplastic cells from the growth observed in the vagina. There were different developmental stages of the merogony of Hepatozoon canis in the bone marrow. We concluded that concurrent hepatozoonosis and TVT and, possibly, the geriatric state of the patient contributed largely to the problem of unresponsiveness to treatment. To the best of our knowledge this is the first report of concurrent infection of canine hepatozoonosis and TVT in Nigeria
References
Gavazza, A., Bizzeti, M. and Papini, R. 2003. Observations on dogs found naturally infected with Hepatozooncanis in Italy. Revue de Medicine Veterinarie, 154 (8/9): 565-571.
Baneth G and Weigler B. 1997. Retrospective case-control study of hepatozoonosis in dogs in Israel. Journal Veterinary internal Medicine 11: 365-370.
Baneth G, Samish M and Shkap V. 2007. Life cycle of Hepatozoon canis (Apicomplexa: Adeleorina: Hepatozoidae) in the tick Rhipicephalus sanguineus and domestic dog (Canis familiaris). Journal of Parasitology, 93 (2): 283-299.
Baneth G, Harmelin A and Presentey BZ. 1995. Hepatozoon canis infection in two dogs. Journal of American Veterinary Medicine, 206: 1891- 1894.
Mascarenhas, M.B.,Peixoto, P.V., Ramadinha, R.R., Yamasaki, E.M., Costa, S.Z.R., Driemeier, D., Sonne, L. and França, T.N. 2014. Immunohistochemical study of genital and extra-genital forms of canine transmissible venereal tumor in Brazil. Pesquisa Veterinária Brasileira, 34(3): 250-254.
Goldschmidt, M.H. and Hendrick, M.J. 2002. Tumours of the skin and soft tissues. In: Textbook of Tumours in Domestic Animals (DJ Meuton, editor). Fourth edition. Iowa, Iowa State Press. 45-118.
Das, U. and Das, A.K. 2000. Review of canine transmissible venereal sarcoma. Veterinary Research Communications, 24 (8): 545–556.
Gupta, K. and Sood, N.K. 2012. Pathological and immunohistochemical studies on rare cases of primary extra-genital transmissible venereal tumours in the mammary gland. Veterinary Medicine of Czech. 57 (4): 198–206.
Bastan, A.D., Baki, A. and Cengiz, M. 2008. Uterine and ovarian metastasis of transmissible venereal tumour in a bitch. Turkey Journal of Veterinary and Animal Science, 32 (1): 65–66.
Baneth G. 2006. Hepatozoonosis. In: Infectious diseases of the dog and cat. 3rd edition, C. E. Greene, W. B. Saunders, Philadelphia, Pensylvania, 698-705.
Voyvoda, H., Pasa, S. and Uner, A. 2004. Clinical Hepatozoon canis infection in a dog in Turkey. Journal of Small Animal Practice, 45: 613-617.
Amaral, A.S., Sandra, B.S. and Isabelle, F. 2007. Cytomorphological characterization of transmissible canine venereal tumor. Revista Portuguesa Ciências Veterinárias, 102 (563-564): 253-260.
Floréz MM, Pedraza F, Grandi F and Rocha NS. 2012. Cytological subtypes of canine transmissible venereal tumor. Veterinary Clinical Pathology 41(1): 3-5.
Ajayi, O.L., Oluwabi, M.,Ajadi, R.A.,Antia, R.E., Omotainse, S.O., Jubril,A.J.,Adebayo, O . O . a n d M a k i n d e , A . F. 2 0 1 8 . Cytomorphological, histopathological and immunohistochemical observations on the histiocytic origin of canine transmissible venereal tumour. Sokoto Journal of Veterinary Sciences, 16(2): 10-20
Erünal-Maral, N., Findik, M. and Aslan, S. 2000. Use of exfoliative cytology for diagnosis of transmissible venereal tumour and controlling the recovery period in the bitch. Dtsch Tierärztl Wochenschr, 107(5): 175-180.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Nigerian Journal of Parasitology
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
