The Nigeria Case Study in NTD Control Efforts
https://doi.org/10.60787/830v-q688
Keywords:
Nigeria, Elimination, Control, Neglected Tropical DiseasesAbstract
Neglected Tropical Diseases (NTDs) are a category of 20 diseases mostly found in the tropics. These diseases are termed neglected because they, unfortunately, receive relatively little attention from national governments and are of low priority for international public health issues. NTDs are endemic in 149 out of 193 countries worldwide, representing 77.2% of the global distribution. More than a billion people, including more than 500 million children, are afflicted by at least one NTD, and 500,000 people die each year because of infections. The global burden of NTDs has brought them to the limelight and consequently resulted in efforts towards controlling and eliminating them, culminating in the WHO 2021 to 2030 road map that targets NTDs for elimination by 2030. The Federal Ministry of Health of Nigeria initiated a program for national NTD control and elimination in 2009. This program focuses on integrated and cost-effective approaches to control and/or eliminate NTDs. As a follow-up to the 2009 national NTD program, Nigeria keyed into the first road map that aimed at the eradication or prevention of transmission by the year 2020 and the second road map which aims to eliminate them by 2030. These have resulted in some modest successes, particularly in the eradication of guinea worm, mapping of onchocerciasis and Lymphatic filariasis as well as mass distribution of drugs. There are several challenges faced in the NTDs control and elimination efforts as identified in this paper and solutions proffered. NTDs in Nigeria still constitute major public health
problems and obstacles to socioeconomic development. It is expected that greater action/commitment will be taken in the
new 2021-2030 road map tagged to achieve the set targets for the elimination of NTDs by the end of 2030.
References
Hotez, P. (2009). Mass drug administration and integrated control for the world’s high-prevalence neglected tropical diseases. Clinical Pharmacology & Therapeutics, 85(6):659–64.
World Health Organization (2010). Updated 2022. Neglected tropical diseases (NTDs). Accessed from: https://www.who.int/health-topics/neglected-tropical-diseases#tab=tab_1
Mitra, A. K. and Mawson, A. R. (2017) Neglected Tropical Diseases: Epidemiology and Global Burden. Tropical Medicine and Infectious Disease, 52(3):36. doi: 10.3390/tropicalmed2030036.
Emeto, D. C., Salawu, A. T., Salawu, M. M. and Fawole, O. I. (2021). Recognition and reporting of neglected tropical diseases by primary health care workers in Ibadan, Nigeria. Pan African Medical Journal, 38:224. doi:10.11604/pamj.2021.38.224.2057
Molyneux, D. H. and Ward, S. A. (2015). Reflections on the Nobel Prize for Medicine 2015 – the public health legacy and impact
of avermectin and artemisinin. Trends in Parasitology, 31(12):605–7.
Herricks, J. R., Hotez, P. J., Wanga, V., Coffeng, L. E., Haagsma, J. A. and Basa´ ñez, M. G. (2013). The global burden of disease study: What does it mean for the NTDs? PLoS Neglected Tropical Diseases, 11 (8): e0005424
Hotez, P. J., Alvarado, M., Basáñez, M. G., Bolliger, I., Bourne, R., Boussinesq, M., Brooker, S. J., Brown, A. S., Buckle, G., Budke, C. M., Carabin, H., Coffeng, L. E., Fèvre, E. M., Fürst, T., Halasa, Y. A., Jasrasaria, R., Johns, N. E., Keiser, J., King, C. H., Lozano, R., Naghavi, M. (2014). The global burden of disease study 2010: interpretation and implications for the neglected tropical diseases. PLoS Neglected Tropical Diseases, 8(7), e2865. https://doi.org/10.1371/journal.pntd.0002865
Ochola, E. A., Elliott, S. J. and Karanja, D. M. S. (2021). The Impact of Neglected Tropical Diseases (NTDs) on Women’s Health and Wellbeing in Sub-Saharan Africa (SSA): A Case Study of Kenya. International Journal of Environmental Research Public Health, 18, 2180. https://doi.org/10.3390/ ijerph18042180
Olsen, A. (2007). Efficacy and safety of drug combinations in the treatment of Schistosomiasis, soil-transmitted helminthiasis, lymphatic filariasis and onchocerciasis. Transactions of the Royal Society of Tropical Medicine and Hygiene, 101(8):747-758.
Brooker, S., Clements, A. C., and Bundy, D. A. (2006). Global epidemiology, ecology and control of soil-transmitted helminth infections. Advances in Parasitology 62:221-61. doi: 10.1016/S0065-308X (05)62007-6.
Lenk, E. J., Redekop, W. K., Luyendijk, M., Rijnsburger, A. J., and Severens, J. L. (2016). Productivity loss related to neglected tropical diseases eligible for preventive chemotherapy: a systematic literature review. PLoS Neglected Tropical Diseases 18, 10(2): e0004397. World Health Organization (2017). Integrating neglected tropical diseases into global health and development: fourth WHO report on neglected tropical diseases. World Health Organization.
World Health Organization (2022). Trachoma. Accessed from: https://www.who.int/news-room/fact-sheets/detail/trachoma
Choi, H. G., Lee, M. J., and Lee, S. M. (2020). Mortality and causes of death in a population with blindness in Korea: A longitudinal follow-up study using a national sample cohort. Science Report, 10(1):4891. doi: 10.1038/s41598-020-61805-6.
Hotez P. J. (2014). The medical biochemistry of poverty and neglect. Molecular medicine (Cambridge, Mass.), 20 Suppl 1(Suppl 1), S31–S36.
https://doi.org/10.2119/molmed.2014.00169
Ramaiah, K. D., Das, P. K., Appavoo, N. C., Ramu, K., Augustin, D. J., Vijay Kumar, K. N., and Chandrakala, A. V. (2000). A programme to eliminate lymphatic filariasis in Tamil Nadu state, India: compliance with annual singledose DEC mass treatment and some related operational
aspects. Tropical Medicine & International Health, 5(12), 842-847.
Nwosu, A. B. C., Ifezulike, E. O., and Anya, A. O. (1982). Endemic dracontiasis in Anambra State of Nigeria: geographical distribution, clinical features, epidemiology and socio-economic impact of the disease. Annals of Tropical Medicine & Parasitology, 76(2), 187-200.
Nwoke, B. E. B. (1990). The socioeconomic aspects of human onchocerciasis in Africa: The present appraisal. Journal of Hygiene,
Epidemiology and Microbiology & Immunology, 34(1): 37-44
Edungbola, L. D. (1983). Babana parasitic diseases project. II. Prevalence and impact of dracontiasis in Babana District, Kwara State, Nigeria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 77(3), 310-315.
Mweetwa, D. (2012). In Zambia, Children of the Blind Lack Education and, Forced to Beg. Global Press Journal. Accessed from:
https://globalpressjournal.com/africa/zambia/in-zambia-children-of-the-blind-lack- education-forced-to-beg/
Gyapong, J. O., Gyapong, M., Evans, D. B., Aikins, M. K., and Adjei, S. (1996). The economic burden of lymphatic filariasis in northern Ghana. Annals of Tropical Medicine & Parasitology, 90(1), 39-48.
Vinkeles Melchers, N. V. S., Stolk, W. A., van Loon, W., Pedrique, B., Bakker, R., Murdoch, M. E., de Vlas, S. J., andCoffeng, L. E. (2021). The burden of skin disease and eye disease due to onchocerciasis in countries formerly under the African Programme for Onchocerciasis Control mandate for 1990, 2020, and 2030. PLoS Neglected Tropical Diseases, 15(7), e0009604. https://doi.org/10.1371/journal.pntd.0009604
Hotez, P. J. and Gurwith, M. (2011). Europe's neglected infections of poverty. International Journal of Infectious Diseases, 15(9), e611-e619.
Engels, D., and Zhou, X. N. (2020). Neglected tropical diseases: an effective global response to local poverty-related disease priorities. Infectious Diseases Poverty 9, 10. https://doi.org/10.1186/s40249-020-0630-9.
Deribe, K., Tomczyk, S., and Tekola- Ayele, F. (2013). Ten years of podoconiosis research in Ethiopia. PLoS Neglected Tropical Diseases, 7(10), e2301.
Keating, C. (2014). Ken Warren and the Rockefeller Foundation's great neglected diseases network, 1978-1988: the transformation of tropical and global medicine. Molecular medicine (Cambridge, Mass.), 20 Suppl 1(Suppl 1), S24–S30. https://doi.org/10.2119/molmed.2014.00221
Hotez, P. J., Le Trang, N., and Cerami, A. (1987). Hookworm antigens: the potential for vaccination. Parasitology Today, 3(8):247–9.
Hawking, F. (1962). A review of progress in the chemotherapy and control of filariasis since 1955. Bulletin of the World Health Organization, 27(4–5):555–68.
Hawking, F. and Marques, R. J. (1967). Control of Bancroftian filariasis by cooking salt medicated with diethylcarbamazine. Bulletin of the World Health Organization, 37(3):405–14.
World Health Organization (2003). Control of lymphatic filariasis in China. Manila: World Health Organization Regional Office for the Western Pacific.
Anderson, R. M. and May, R. M. (1982). Population dynamics of human helminth infections: control by chemotherapy. Nature, 297(5867):557–63.
Schad, G. A. and Anderson, R. M. (1985). Predisposition to hookworm infection in humans. Science, 228(4707):1537–40.
World Bank. Forty years later: the extraordinary river blindness partnership sets its sights on new goals. Available from: https://www.worldbank.org/en/news/feature/2014/07/03/forty-years-later-the-extraordinary-river-blindness-partnership-sets-its-sights-
onnew- goals [accessed 22 July 2020].
Molyneux, D. (1995). Onchocerciasis control in West Africa: current status and future of the Onchocerciasis Control Programme. Parasitology Today, 11:399–402. CDI Study Group (2010). Community- directed interventions for priority health problems in Africa: results of a multicounty
study. Bulletin of the World Health Organization, 88(7):509–18.
Cross, C. (2009). The role of NGDOs in disease elimination programmes: the lessons from onchocerciasis control. Transactions of the Royal Society of Tropical Medicine & Hygiene, 94:601–2.
Horton, J. (2002). Albendazole: a broad spectrum anthelminthic for treatment of individuals and populations. Current Opinions in Infectious Diseases, 15(6):599–608.
Davis, A. and Wegner, D. H. (1979). Multicenter trials of praziquantel in human schistosomiasis: design and techniques. Bulletin of the World Health Organization 57(5):767–71.
Ottesen, E. A., Duke, B. O., Karam, M., and Behbehani, K. (1997). Strategies and tools for the control/elimination of lymphatic filariasis. Bulletin of the World Health Organization, 75(6):491–503.
World Health Organization (2020). Vector-borne diseases. https://www.who.int/news-room/fact-sheets/detail/vector-borne-diseases.
Pan African Health Organization (2007). Global Plan to Combat Neglected Tropical Diseases, 2008-2015. Accessed from:
https://www3.paho.org/hq/index.php?option=com_content&view=article&id=5704:2011-global-plan-combat-neglected-tropical-diseases-20082015&Itemid=0&lang=en#gsc.tab=0 World Health Organization (2021). WHO launches a new road map to prevent, control, eliminate and eradicate 20 neglected tropical diseases by 2030. Accessed from: https://www.emro.who.int/media/news/who-launches-new-road-map-to-prevent-control-eliminate-and-eradicate-20-neglected-tropical-diseases-by-2030.html
World Health Organization (2022). WHO meeting discusses new strategies to tackle skin NTDs in West Africa Accessed from: https://www.who.int/news/item/11-10-2022-who-meeting-discusses-new-strategies-to-tackle-skin-ntds-in-west-africa.
Lakwo, T., Oguttu, D., Ukety, T., Post, R., and Bakajika, D. (2020). Onchocerciasis Elimination: Progress and Challenges. Research and Reports in Tropical Medicine, 11, 81–95. https://doi.org/10.2147/RRTM.S224364
Okorie, P. N., Ademowo, G. O., Saka, Y., Davies, E., Okoronkwo, C., Bockarie, M. J., Molyneux, D. H., and Kelly-Hope, L. A. (2013) Lymphatic filariasis in Nigeria; micro-stratification overlap mapping (MOM) as a prerequisite for cost-effective resource utilization in control and
surveillance. PLoS Neglected Tropical Diseases 5, 7(9):e2416. doi: 10.1371/journal.pntd.0002416.
World Health Organization (2020). Lymphatic filariasis: reporting continued progress towards elimination as a public health problem. Accessed from: https://www.who.int/news/item/29-10- 2020-lymphatic-filariasis-reporting-continued-progress-towards-elimination-as-a-public-health-problem.
Bakowski, M. A., and McNamara, C. W. (2019). Advances in Antiwolbachial Drug Discovery for Treatment of Parasitic Filarial Worm Infections. Tropical Medicine & Infectious Diseases18, 4(3):108. doi: 10.3390/tropicalmed4030108.
Macfarlane, C.L., Budhathoki, S.S., Johnson, S., Richardson, M., and Garner, P. (2019). Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis. Cochrane Database Systematic Reviews. 8;1(1):CD003753. doi: 10.1002/14651858.
World Health Organization (2010). Updated 2022. Neglected tropical diseases (NTDs). Accessed from: https://www.who.int/health-Citation
Dozie, I. N. S. (2023). The Nigeria Case Study in NTD Control Efforts Nigerian Journal of Parasitology, Special Issue No. 1, December, 2023
topics/neglected-tropical- diseases#tab=tab_1
Drake, L. J., Singh, S., Mishra, C. K., Sinha, A., Kumar, S., Bhushan, R., Hollingsworth, T. D., Appleby, L. J., Kumar, R., Sharma, K., Kumar, Y.,
Raman, S., Chakrabarty, S., Kihara, J. H., Gunawardena, N. K., Hollister, G., Kumar, V., Ankur, A., Prasad, B., Ramachandran, S., Fishbane, A., and
Makkar, P. (2015). Bihar's Pioneering School-Based Deworming Programme: Lessons Learned in Deworming over 17 Million Indian School-Age Children in One Sustainable Campaign. PLoS Neglected Tropical Diseases, 9(11), e0004106. https://doi.org/10.1371/journal.pntd.00041
https://doi.org/10.1371/journal.pntd.0004106.
World Health Organization (2021). WHO partners Borno State in fight against Leishmaniasis. Accessed from: https://www.afro.who.int/news/who-partners- borno-state-fight-against-leishmaniasis.
Nwoke, B. E. B. (2023). Working towards the NTD road map 2030 targets for onchoerciasis elimination in Nigeria. Presented to WHO Global Onchocerciasis Network for Elimination (GONE). January 19, 2023 (Unpublished), WHO/AFRO, Harare.
Mercandalli, S., Losch, B., Rapone, C., Bourgeois, R., and Khalil, C. A. (2017). Rural migration and the new dynamics of structural transformation in sub-saharan Africa. Food and Agriculture Organization of the United Nations Rome. https://www.fao.org/3/ca7404en/CA7404E
N.pdf.
Downloads
Published
How to Cite
Issue
Section
Categories
License
Copyright (c) 2024 Nigerian Journal of Parasitology
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.